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pearls 1
most commonly associated with bladder rupture=Blunt trauma with a full bladder [ as don't drive with a full bladder]
following groups of predisposing factors is most likely to be associated with carcinoma of the colon:=High-fat diet; ulcerative colitis; diet low in vitamins A, E, C and selenium; Crohn's disease
A low-fiber diet, not a high-fiber diet, is associated with an increased incidence of colon cancer and diverticular disease.
Additional predisposing or risk factors for colon cancer are a
high-fat diet,
familial polyposis syndromes,
ulcerative colitis,
Crohn's disease,
and a diet low in antioxidant vitamins (i.e., A, C, E)
and selenium.
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 Primary amenorrhea can be classified into four groups based on the presence or absence of normal breast development and a palpable uterus.
 woman, with normal breast development but without a uterus, has either:
testicular feminization syndrome
or congenital uterine absence.
a genetic male has a congenital lack of androgen receptors, and so the normal male levels of testosterone are unrecognized.
Normal female hormonal status is associated with congenital uterine absence, including low levels of testosterone. Thus, measurement of serum testosterone would be the most useful test
 Follicle-stimulating hormone (FSH) is helpful for differentiating the etiology of primary amenorrhea with absent breasts but uterus present.
 An elevated FSH level indicates absence of functional follicles, whereas a low FSH level indicates a hypothalamic-pituitary problem.
 Luteinizing hormone (LH) is not helpful because it normally fluctuates significantly during a normal menstrual cycle.
 Prolactin and progesterone levels do not contribute to the work-up of primary amenorrhea.
woman comes to the physician's office stating that she has never had a menstrual period. Physical examination reveals normal breast development, but no uterus can be palpated on pelvic examination.- tests for serum levels would be most helpful in identifying the cause of her amenorrhea:Testosterone
Externally, she looks like the perfect woman: voluptuous, tall, clear complected, luxuriant hair. Internally, however, things get a little more complicated. Because of Androgen Insensitivity Syndrome (AIS), on the outside she appears as a woman, but on the inside she has testes instead of ovaries and a uterus. AIS is the inability to utilize the androgens produced by the embryonic testes, so the fetus develops as male (XY) until it is time for the sex organs to mature further. The external genitalia appear female, but internally the testes produce another hormone which inhibits the development of female organs. Because she has no ovaries or uterus, she cannot menstruate or have children
Testicular-Feminization Syndrome
- XY individuals
- female with few traces of masculinity
- sterile
- mutation on X chromosome
- due to inability of embryonic tissue to respond to testosterone
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Classification
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Definition
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Normospermia
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Normal ejaculate as defined in Table 2
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Oligozoospermia
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Sperm concentration <20 x 106/ml
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Asthenozoospermia
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Fewer than 50% spermatozoa with forward progression or fewer than 25% spermatozoa with rapid linear progression
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Teratozoospermia
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Fewer than 30% spermatozoa with normal morphology
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Oligoasthenoteratozoospermia
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Signifies disturbance of all three variables (combination of only two prefixes may also be used)
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Azoospermia
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No spermatozoa in the ejaculate
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Aspermia
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No ejaculate
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1/
 23-year-old woman, gravida 2, para 1, at 14 weeks' gestation has a 6-cm unilateral, unilocular pelvic mass.
 The mass is separate from the uterus and has been confirmed by serial sonograms.
 However, it is variable in location, being noted anterior, posterior, and lateral to the uterus
The case scenario describes a hydatid cyst of Morgagni, also known as a paraovarian cyst.
They are thin-walled, pedunculated, benign cysts attached to the tubal fimbria.
They are of paramesonephric origin and are usually small, but they can grow to 10 cm in size and can be very mobile.
2/34-year-old woman, gravida 1, para 0, at 18 weeks' gestation with severe hyperemesis
has a blood pressure of 150/95 mm Hg, 2+ proteinuria,
and bilateral adnexal masses that are 8 cm in diameter and are multiloculated on a sonogram
The case scenario describes theca-lutein cysts,
which occur as a response of normal ovaries to excessively high b-human chorionic gonadotropin (HCG) titers
which, in this case, are a result of a molar pregnancy associated with preeclampsia before 20 weeks' gestation.
The cysts are bilateral and fluid-filled, growing to massive size.
They disappear when the source of the increased b-HCG levels is resolved.
3/An 18-year-old woman, gravida 1, now para 1, just delivered a 3500-g (7 lb 12 oz) healthy male neonate without complications.
At 8 weeks' gestation, she was noted to have a 5-cm right adnexal cystic mass that spontaneously disappeared and was no longer seen on sonogram at 16 weeks' gestation.
The case scenario describes a classic corpus luteum cyst of pregnancy that resolved spontaneously when the placenta took over the function of progesterone production.
These cysts are generally unilateral.
4/A 29-year-old woman had her last menses 9 weeks ago.
She is noted to have a 9- to 10-cm soft, midline pelvic mass.
She has experienced morning nausea, but no vomiting
= pregnancy
The case scenario describes a normal intrauterine pregnancy.
This is the most common cause of an enlarged pelvic mass in the reproductive years.
5/A 5-year-old girl, who shows signs of isosexual complete precocious puberty, is found to have a 4-cm unilateral, solid pelvic mass
The case scenario describes a child undergoing precocious puberty with the finding of a unilateral pelvic mass.
This must be assumed to be a hormonally functional ovarian tumor producing estrogen,
such as a granulosa cell tumor, until proved otherwise.
6/A 55-year-old postmenopausal woman shows evidence of
temporal balding,
clitoromegaly,
and increased facial hair.
She is noted to have a 5-cm unilateral, solid pelvic mass.
=Sertoli-Leydig cell tumor
balding + hair think men think androgen think tumor like men do have = sertoli
The case scenario describes a postmenopausal woman with virilization and a unilateral pelvic mass.
This must be assumed to be a hormonally functional ovarian tumor producing androgens,
such as a Sertoli-Leydig cell tumor, until proved otherwise.
7/28-year-old nulligravid woman is found on routine annual examination to have a 6-cm unilateral pelvic mass.
On sonogram, the mass is partially solid and partially cystic with foci of calcifications.
=Benign cystic teratoma
The case scenario describes a benign cystic teratoma.
Because these tumors derive from primordial germ cells, they may contain any combination of
well-differentiated ectodermal,
mesodermal,
and endodermal elements.
Foci of calcification, even the presence of teeth, are common.
8/A 32-year-old infertile, obese nulligravida is noted to have an asymptomatic 7-cm right adnexal mass.
She has uterosacral ligament nodularity and a fixed retroverted uterus.
=endometrioma
The case scenario is characteristic for endometriosis.
Endometriomas are cysts on the ovary that result from accumulation of menstrual-like detritus from endometriosis.
These "chocolate cysts'' can enlarge to many centimeters in size.
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